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Calquence will be the first all-oral, fixed-duration regimen for CLL and SLL in the U.S.
February 20, 2026
By: Patrick Lavery
Content Marketing Editor
The FDA has approved AstraZeneca’s Calquence (acalabrutinib), for adult patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Combined with venetoclax (brand name Venclexta, Abbvie/Genentech), it is the U.S.’ first all-oral, fixed-duration regimen for CLL and SLL. In a press release, AstraZeneca said that results from a Phase III trial (AMPLIFY) informed the FDA’s decision. These results were presented at the American Society of Hematology 2024 and published i...
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